Publications

Books

  1. Ashley, CC Campbell,AK (eds).(1979). The detection and measurement of free Ca2+in cells. pp 461 Elsevier/North Holland, Amsterdam.
  2. Campbell,AK. (1983)Intracellular Calcium: its universal role as regulator. pp 556. John Wiley and Sons:Chichester.
  3. Campbell,AK. (1988). Chemiluminescence: principles and applications in biology and medicine, pp608. Horwood/VCH, Chichester and Weinheim.
  4. Herring,PJ, Campbell,AK, Whitfield, M and Maddock, L (eds) (1990). Light and Life in the Sea. pp 357. Cambridge University Press, Cambridge.
  5. Campbell,AK. (1994). Rubicon: the fifth dimension of biology. pp 304. Duckworth, London.
  6. Campbell, AK, Kricka, LJ and Stanley, PE ed. (1994). Bioluminescence and Chemiluminescence: fundamental and applied aspects. pp 680. Wiley, Chichester.
  7. Campbell, AK and Matthews, SB (2001). Lactose intolerance and the MATHS:syndrome: what are they and how can I cope? Pp 32. Welston Press, Pembrokeshire. ISSN 1474-6794, ISBN 0-9540866-0-0).
  8. Campbell, AK and Matthews, SB (2005). Tony's lactose free recipe book - the science of lactose intolerance and how to live without lactose. The Welston Press, Pembrokeshire. ISBN 0-9540866-1-9.

 

Key scientific papers

  1. Campbell,AK. (1974)Biochem. J. 143:411-418. Extraction, partial purification and properties of obelin, the calcium- activated luminescent protein from the hydroid Obelia geniculata.
  2. Simpson,JSA Campbell,AK Ryall,MET Woodhead,JS. (1979). Nature (London). 279:646-647. A stable chemiluminescent-labelled antibody for immunological assays.
  3. Hallett,MB Campbell,AK. (1982). Nature 295: 155-158. Measurement of changes in cytoplasmic free Ca in fused cell hybrids.
  4. Campbell,AK and Morgan,BP. (1985). Nature 317:164-166. Monoclonal antibodies demonstrate protection of polymorphonuclear leucocytes against complement attack.
  5. Campbell,AK Patel,AK Razavi,ZS McCapra,F. (1988) Biochem. J. 252:143-149. Formation of the Ca2+ -activated photoprotein from obelin and mRNA inside human neutrophils.
  6. Scolding,NJ Morgan,BP Houston,WAJ Linington,C Campbell,AK Compston,DAS. (1989) Nature 339:690-692. Oligodendrocytes activate complement but resist lysis by vesicular removal of membrane attack complexes.
  7. Campbell,AK Herring,PJ. (1990) Marine Biology 104:219-225. Imidazolopyrazine bioluminescence in copepods and other marine animals.
  8. Davies,EV, Campbell,AK, Williams,BD and Hallett,MB (1991) Br.J.Rheum.30:443-448. Single cell imaging reveals abnormal intracellular calcium stores within rheumatoid synovial neutrophils.
  9. Sala-Newby,G and Campbell,AK (1991) Biochem.J. 279:727-732. Engineering a bioluminescent indicator for cyclic AMP dependent protein kinase .
  10. Knight,MR, Campbell,AK, Smith,SM and Trewavas,AJ (1991) Nature 352:524-526. Transgenic tobacco aequorin reports touch, cold-shock and elicitor effects on cytoplasmic calcium.
  11. Knight, MR, Read, ND, Campbell, AK and Trewavas, AJ. (1993). J. Cell Biol. 121:83-90. Imaging calcium dynamics in living plants using semi-synthetic recombinant aequorins.
  12. Watkins, NJ, Knight MR, Trewavas, AJ and Campbell AK (1995). Biochem. J. 306:865-869. Free calcium transients in chemotactic and non-chemotatcic strains of Escherichia coli determined by using recombinant aequorin.
  13. Thomson, CM, Herring, PJ and Campbell AK (1995) J Mar Biol Assoc. 75:165-171. Evidence for de novo synthesis of coelenterazine in the bioluminescent midwater shrimp Systellaspis debilis.
  14. Trewavas, AJ, Knight, MR and Campbell,AK (1995). Proc. Natl. Acad. Sci. US 92:4142-4128. The effects of mechanical signalling on plant cell cytosolic calcium.
  15. Sala-Newby, GB, Thomson, CM and Campbell, AK (1996). Biochem. J. 313: 761-767. Sequence and biochemical similarities between luciferases of the glow-worm Lampyris noctiluca and the firefly Photinus pyralis.
  16. Waud, J, Sala-Newby, GB and Campbell, AK (1996). Biochim. Biophys. Acta 1292:89-98. Engineering the C-terminus of firefly luciferase as an indicator of covalent modification of proteins.
  17. Campbell, AK, Trewavas, AJ and Knight, MR (1996). Calcium imaging shows differential sensitivity to cooling and communication in luminous transgenic plants. Cell Calcium 19: 211-218.
  18. Llewelyn, DH, Roderick, L, Sheik, N and Campbell, AK (1996). Biochem.J.318:400-410. Calcium stress induces calreticulin gene expression.
  19. Kendall, JM, Sala-Newby, G Badminton, M, Campbell AK and Rembold, CR (1996). Free Ca2+ in the endoplasmic reticulum of living cells measured using aequorin as a pseudo luciferase. Biochem.J 318:383-387
  20. Badminton, MN, Campbell, AK and Rembold, CR (1996). J.Biol. Chem. 271:31210-31214. Differential regulation of nuclear and cytosolic Ca2+ in HeLa cells.
  21. Sala Newby, GB, Taylor, KT, Badminton, MN, Rembold, CR and Campbell, AK (1998). Imaging bioluminescent indicators shows Ca2+ and ATP permeability thresholds in live cells attacked by complement. Immunology. 93:4:601-609.
  22. Roderick HL, Llewellyn DH, Campbell AK and Kendall JM (1998). Role of calreticulin in regulating intracellular Ca2+ storage and capacitative Ca2+ entry in HeLa cells. Cell Calcium 24:253-262
  23. Jones HE, Holland IB, Baker HL, Campbell AK (1999). Slow changes in cytosolic free Ca2+ in Escherichia Coli highlight two putative influx mechanisms in response to changes in extracellular calcium. Cell Calcium 25:3:265-274.
  24. Dunstan, S, Sala-Newby, GB, Bermudez-Fajardo, A, Taylor, K.M. and Campbell, A.K. (2000). Cloning and expression of the bioluminescent photoprotein pholasin from the bivalve mollusc Pholas dactylus. J.Biol.Chem.275, 9403-9409.
  25. Matthews, SB and Campbell, AK (2000). When sugar is not so sweet. Lancet 355:1330.
  26. Baubet,V, Le Mouellic, H, Campbell, AK, Lucas-Meunier, E, Fossier, P and Brulet, P (2000). Chimeric GFP-aequorin as bioluminescent Ca2+ reporters at the single cell level. Proc.Natl.Acad.Sci.97:7260-7265.
  27. Waud, J, Bermudez-Fajardo, A, Sudadhaharan, T, Jefferies, J, Jones, A,Campbell, AK (2001). Measurement of proteases using chemiluminescence resonance energy transfer chimaeras between green fluorescent protein and aequorin. Biochem.J. 357: 687-697.
  28. Baker HL, Errington RJ, Davies SC and Campbell AK. (2002). A Mathematical Model Predicts that Calreticulin Interacts with the Endoplasmic Reticulum Ca2+-ATPase. Biophysical Journal 82:582-590
  29. Chapuy-Regaud S, Jones HE, Campbell AK, Trombe MC (2001). Validation of the use of aequorin for cytoplasmic free calcium determination by chemiluminescence in Streptococcus pneumoniae. J Soc Biol 195:271-6
  30. Smith PJ, Wiltshire M, Davies S, Chin SF, Campbell AK, Errington RJ. (2002). DNA damage-induced [Zn(2+)](i) transients: correlation with cell cycle arrest and apoptosis in lymphoma cells. Am J Physiol Cell Physiol. 283(2):C609-22
  31. H. E. Jones, I. B. Holland, A. K. Campbell (2002). Direct measurement of free Ca2+ shows different regulation of Ca2+ between the periplasm and the cytosol of Escherichia coli. Cell Calcium. 32(4):183-192
  32. Campbell AK (2003). Save those molecules! Molecular biodiversity and life. Journal of Applied Ecology. 40:193-203
  33. Jones HE, Holland IB, Jacq A, Wall T and Campbell AK (2003) Escherichia coli lacking the AcrAB multi-drug efflux pump also lacks non-proteinaceous, PHB-polyphosphate Ca2+ channels in the membrane. Biochem Biophys Acta Biomembranes. 1612:90-97
  34. Campbell AK (2003). What Darwin missed. Astrophysics and Space Science 285:1-5
  35. Campbell AK (2003). Rainbow Makers. Chemistry in Britain June 2003:30-33
  36. Campbell AK (2003). Dr Darwin's Botanical Garden. Nature First 32:11
  37. Matthews SB, Campbell AK. Lactose Intolerance in the Young: A New Perspective. Welsh Paediatric J. 2004; 20:56-66.
  38. Campbell, AK, Matthews, SB and Wann, KT (2004). Lactose causes heart arrhythmia in the water flea Daphnia pulex. Comp. Biochem. Physiol. B 139;225-234.
  39. Matthews SB, Waud J, Roberts A and Campbell AK (2005). Systemic lactose intolernace: a new perspective on an old problem. Post Grad. Med. J. 81:167-183.
  40. Campbell, AK and Matthews, SB (2005). Darwin's illness revealed. Post. Grad. Med. J. 81,246-151.
  41. Campbell, AK, Jenkins-Waud, J and Matthews, SB (2005). The Molecular Basis of Lactose intolerance. Science Progress 88, 157-202.
  42. Campbell, AK, Naseem, R, Wann, KT, Holland, IB and Matthews, SB (2006). Fermentation product butane 2,3 diol induces Ca2+ transients in E. coli through activation of lanthanum-sensitive Ca2+ channels. Cell Calcium 41,97-106.

 

Recent key reviews

  1. Sala Newby, GB, Kendall, JM, Jones, H, Taylor, KM, Badminton, MN, Llewellyn, DH and Campbell, AK (1999). Bioluminescent and chemiluminescent indicators for molecular signalling and function in living cells. pp 251-272 In Fluorescent probes for biological function 2nd edition. Ed Mason, WT. Academic Press, London.
  2. Sala-Newby, GB, Badminton, MN, Evans, WH, George, CH, Jones, HE, Kendall, JM, Ribeiro, AS and Campbell, AK (2000). Targeted Bioluminescent indicators in living cells. Methods in Enzymology. 305,478-498.
  3. Campbell AK (2003). What Darwin missed. Astrophysics and Space Science 285:1-5
  4. Campbell AK (2003). Rainbow Makers. Chemistry in Britain June 2003:30-33
  5. Campbell AK (2003). Dr Darwin's Botanical Garden. Nature First 32:11
  6. Campbell AK (2003). Imaging genetically engineered Rainbow proteins. The Pezcoller Foundation Journal. 20:20-22.
  7. Campbell AK (2003). Save those molecules! Molecular biodiversity and life. Journal of Applied Ecology. 40:193-203
  8. Campbell, AK, Jenkins-Waud, J and Matthews, SB (2005). The Molecular Basis of Lactose intolerance. Science Progress 88, 157-202.